Home Amplifiers Fully differential amplifiers
Home
Amplifiers
Fully differential amplifiers

THS4521

ACTIVE

Very low power rail-to-rail output fully differential amplifier

Order now
Data sheet

A newer version of this product is available

open-in-new Compare alternates
Pin-for-pin with same functionality to the compared device
THS4551 ACTIVE Low Noise, Precision, 150MHz, Fully Differential Amplifier Wider bandwidth (BW) (135 MHz), lower noise (3.3 nV/√Hz) and higher precision (0.175 mV)

THS4521

ACTIVE
Data sheet Order now

Product details

Number of channels 1 Total supply voltage (+5 V = 5, ±5 V = 10) (min) (V) 2.5 Total supply voltage (+5 V = 5, ±5 V = 10) (max) (V) 5.5 BW at Acl (MHz) 145 Acl, min spec gain (V/V) 1 Slew rate (typ) (V/µs) 490 Architecture Bipolar, Fully Differential ADC Driver Vn at flatband (typ) (nV√Hz) 4.6 Iq per channel (typ) (mA) 1.14 Rail-to-rail In to V-, Out Vos (offset voltage at 25°C) (max) (mV) 2 Operating temperature range (°C) -40 to 85 Iout (typ) (mA) 55 2nd harmonic (dBc) 133 3rd harmonic (dBc) 141 Frequency of harmonic distortion measurement (MHz) 0.001 GBW (typ) (MHz) 95 Input bias current (max) (pA) 900000 Features Shutdown CMRR (typ) (dB) 102 Rating Catalog
Number of channels 1 Total supply voltage (+5 V = 5, ±5 V = 10) (min) (V) 2.5 Total supply voltage (+5 V = 5, ±5 V = 10) (max) (V) 5.5 BW at Acl (MHz) 145 Acl, min spec gain (V/V) 1 Slew rate (typ) (V/µs) 490 Architecture Bipolar, Fully Differential ADC Driver Vn at flatband (typ) (nV√Hz) 4.6 Iq per channel (typ) (mA) 1.14 Rail-to-rail In to V-, Out Vos (offset voltage at 25°C) (max) (mV) 2 Operating temperature range (°C) -40 to 85 Iout (typ) (mA) 55 2nd harmonic (dBc) 133 3rd harmonic (dBc) 141 Frequency of harmonic distortion measurement (MHz) 0.001 GBW (typ) (MHz) 95 Input bias current (max) (pA) 900000 Features Shutdown CMRR (typ) (dB) 102 Rating Catalog
SOIC (D) 8 29.4 mm² 4.9 x 6 VSSOP (DGK) 8 14.7 mm² 3 x 4.9
  • Fully Differential Architecture
  • Bandwidth: 145 MHz (AV = 1 V/V)
  • Slew Rate: 490 V/µs
  • HD2: –133 dBc at 10 kHz (1 VRMS,
    RL = 1 kΩ)
  • HD3: –141 dBc at 10 kHz (1 VRMS,
    RL = 1 kΩ)
  • Input Voltage Noise: 4.6 nV/√Hz
    (f = 100 kHz)
  • THD+N: –112dBc (0.00025%) at
    1 kHz (22-kHz BW, G = 1, 5 VPP)
  • Open-Loop Gain: 119 dB (DC)
  • NRI–Negative Rail Input
  • RRO–Rail-to-Rail Output
  • Output Common-Mode Control
    (with Low Offset)
  • Power Supply:
    • Voltage: +2.5 V (±1.25 V) to
      +5.5 V (±2.75 V)
    • Current: 1.14 mA/ch
  • Power-Down Capability: 20 µA (typical)
  • Fully Differential Architecture
  • Bandwidth: 145 MHz (AV = 1 V/V)
  • Slew Rate: 490 V/µs
  • HD2: –133 dBc at 10 kHz (1 VRMS,
    RL = 1 kΩ)
  • HD3: –141 dBc at 10 kHz (1 VRMS,
    RL = 1 kΩ)
  • Input Voltage Noise: 4.6 nV/√Hz
    (f = 100 kHz)
  • THD+N: –112dBc (0.00025%) at
    1 kHz (22-kHz BW, G = 1, 5 VPP)
  • Open-Loop Gain: 119 dB (DC)
  • NRI–Negative Rail Input
  • RRO–Rail-to-Rail Output
  • Output Common-Mode Control
    (with Low Offset)
  • Power Supply:
    • Voltage: +2.5 V (±1.25 V) to
      +5.5 V (±2.75 V)
    • Current: 1.14 mA/ch
  • Power-Down Capability: 20 µA (typical)

The THS4521, THS4522, and THS4524 family of devices are very low-power, fully differential amplifiers with rail-to-rail output and an input common-mode range that includes the negative rail. These amplifiers are designed for low-power data acquisition systems and high-density applications where power dissipation is a critical parameter, and provide exceptional performance in audio applications.

The family includes single FDA (THS4521), dual FDA (THS4522), and quad FDA (THS4524) versions.

These fully differential amplifiers feature accurate output common-mode control that allows for dc-coupling when driving analog-to-digital converters (ADCs). This control, coupled with an input common-mode range below the negative rail as well as rail-to-rail output, allows for easy interfacing between single-ended, ground-referenced signal sources. Additionally, these devices are ideally suited for driving both successive-approximation register (SAR) and delta-sigma (ΔΣ) ADCs using only a single +2.5V to +5V and ground power supply.

The THS4521, THS4522, and THS4524 family of fully differential amplifiers is characterized for operation over the full industrial temperature range from –40°C to +85°C.

The THS4521, THS4522, and THS4524 family of devices are very low-power, fully differential amplifiers with rail-to-rail output and an input common-mode range that includes the negative rail. These amplifiers are designed for low-power data acquisition systems and high-density applications where power dissipation is a critical parameter, and provide exceptional performance in audio applications.

The family includes single FDA (THS4521), dual FDA (THS4522), and quad FDA (THS4524) versions.

These fully differential amplifiers feature accurate output common-mode control that allows for dc-coupling when driving analog-to-digital converters (ADCs). This control, coupled with an input common-mode range below the negative rail as well as rail-to-rail output, allows for easy interfacing between single-ended, ground-referenced signal sources. Additionally, these devices are ideally suited for driving both successive-approximation register (SAR) and delta-sigma (ΔΣ) ADCs using only a single +2.5V to +5V and ground power supply.

The THS4521, THS4522, and THS4524 family of fully differential amplifiers is characterized for operation over the full industrial temperature range from –40°C to +85°C.
filter Find other Fully differential amplifiers
Download View video with transcript Video

Technical documentation

star =Top documentation for this product selected by TI
No results found. Please clear your search and try again.
View all 15
Type Title Date
* Data sheet THS452x Very Low Power, Negative Rail Input, Rail-To-Rail Output, Fully Differential Amplifier datasheet (Rev. H) PDF | HTML 18 Jun 2015
Circuit design High-speed overcurrent detection circuit (Rev. B) PDF | HTML 02 Oct 2024
E-book The Signal e-book: A compendium of blog posts on op amp design topics 28 Mar 2017
Application note Fully-Differential Amplifiers (Rev. E) 19 Sep 2016
More literature Featured High Speed Differential Amplifiers 23 Oct 2012
Analog Design Journal Converting single-ended video to differential video in single-supply systems 16 Sep 2011
Analog Design Journal Using single-supply fully diff. amps with neg. input voltages to drive ADCs 15 Nov 2010
Application note DC Output Errors in a Fully-Differential Amplifier 25 May 2010
Analog Design Journal Using fully differential op amps as attenuators, Part 3 04 Oct 2009
EVM User's guide THS4521/45222/4524EVM User's Guide 16 Jul 2009
Analog Design Journal Using fully differential op amps as attenuators, Part 2 14 Jul 2009
Analog Design Journal Using fully differential op amps as attenuators, Part 1 01 May 2009
Analog Design Journal Analysis of fully differential amplifiers 11 Mar 2005
Analog Design Journal Designing for low distortion with high-speed op amps 02 Mar 2005
Application note Noise Analysis for High Speed Op Amps (Rev. A) 17 Jan 2005

Design & development

For additional terms or required resources, click any title below to view the detail page where available.

Evaluation board

REF6025EVM-PDK — REF6025 voltage reference evaluation module

The REF6025EVM-PDK is a platform for evaluating the performance of the REF6025 voltage reference. The evaluation kit brings out the burst mode performance of the device which is a key feature of the device.
User guide: PDF
Not available on TI.com
Evaluation board

THS4521EVM — THS4521 evaluation module

The THS4521EVM is an evaluation module for the single, THS4521 in the D (8-lead SOIC) package.

The THS4521EVM is designed to quickly and easily demonstrate the functionality and versatility of the amplifier. The EVM is ready to connect to power, signal source, and test instruments through the use of (...)

User guide: PDF
Not available on TI.com
Simulation model

THS4521 PSpice Model (Rev. E)

SBOM343E.ZIP (36 KB) - PSpice Model
Download
Simulation model

THS4521 TINA-TI Reference Design (Rev. E)

SBOM341E.TSC (1619 KB) - TINA-TI Reference Design
Download
Simulation model

THS4521 TINA-TI Spice Model (Rev. D)

SBOM342D.ZIP (16 KB) - TINA-TI Spice Model
Download
Calculation tool

SBOR022 — TI FDA Calculator

Supported products & hardware

Supported products & hardware

Products
Fully differential amplifiers
LMH6550 — 400MHz, Differential, High Speed Op Amps LMH6551 — 370MHz, Differential, High Speed Op Amp LMH6552 — 1.5 GHz Fully Differential Amplifier LMH6553 — 900 MHz Fully Differential Amplifier with Output Limiting Clamp LMH6554 — 2.8 GHz Ultra Linear Fully Differential Amplifier LMP8350 — Ultra Low Distortion Fully Differential Precision ADC Driver with Selectable Power Modes OPA862 — 12.6V, Low-noise, single-ended-to-differential, high input impedance amplifier THS4120 — 3.3 V, 100 MHz, 43 V/us, Fully Differential CMOS Amplifier w/Shutdown THS4121 — 3.3 V, 100 MHz, 43 V/us, Fully Differential CMOS Amplifier THS4130 — 150MHz, Fully Differential Input/Output Low Noise Amplifier With Shutdown THS4131 — Fully Differential Input/Output Low Noise Amplifier THS4140 — 160MHz, Fully Differential Input/Output High Slew Rate Amplifier With Shutdown THS4141 — 160MHz, Fully Differential Input/Output High Slew Rate Amplifier THS4150 — 150MHz, Fully Differential Input/Output High Slew Rate Amplifier With Shutdown THS4151 — 150MHz, Fully Differential Input/Output High Slew Rate Amplifier THS4500 — 15V, High-Speed Fully Differential Amplifier with power-down THS4501 — High-Speed Fully Differential Amplifier, +/-5 V THS4503 — High-Speed Fully-Differential Amplifiers THS4504 — Wideband, Low Distortion Fully Differential Amplifier with Shutdown THS4505 — Wideband, Low-Distortion Fully Differential Amplifier THS4508 — Wideband Fully Differential Amplifier THS4509 — 1.9-GHz, Wideband, Low-Noise, Low-Distortion, Fully-Differential Amplifier THS4511 — 1.6-GHz, unity-gain stable, wideband, low-noise, low distortion fully differential amplifier THS4513 — 1.6-GHz, min gain 1-V/V, low-noise, low distortion fully differential amplifier THS4520 — Rail-to-Rail Output Wideband Fully Differential Amplifier THS4521 — Very low power rail-to-rail output fully differential amplifier THS4522 — Very low power dual channel rail-to-rail output fully differential amplifier THS4524 — Very low power quad channel rail-to-rail output fully differential amplifier THS4531 — Ultra low power 0.25mA, RRO, fully differential amplifier THS4531A — Ultra Low Power, RRO, Fully-Differential Amplifier THS4532 — Dual, Ultra low power 0.25mA, RRO, fully differential amplifier THS4541 — High-Speed Differential I/O Amplifier THS4551 — Low Noise, Precision, 150MHz, Fully Differential Amplifier THS4552 — Dual Channel, Low-Noise, Precision, 150-MHz, Fully Differential Amplifier THS4561 — Low-power, 60-MHz, wide-supply-range fully differential amplifier THS4567 — 220-MHz CMOS input fully differential amplifier with VICM and VOCM control THS770006 — High-Speed Fully Differential ADC Driver Amplifier with +6dB Fixed Gain
Audio op amps
OPA1637 — High-fidelity, high-voltage (36-V), low-noise (3.7-nV/rtHz) Burr-Brown™ audio fully-differential amp
Precision op amps (Vos<1mV)
THP210 — High precision (40-μV, 0.1μV/C), high-voltage (36-V), low-noise (3.7-nV/√Hz), fully-differential amp
RF FDAs
LMH3401 — 7-GHz, Ultra-Wideband, Fully Differential Amplifier LMH5401 — 8-GHz Ultra wideband fully differential amplifier
Download
Simulation tool

PSPICE-FOR-TI — PSpice® for TI design and simulation tool

PSpice® for TI is a design and simulation environment that helps evaluate functionality of analog circuits. This full-featured, design and simulation suite uses an analog analysis engine from Cadence®. Available at no cost, PSpice for TI includes one of the largest model libraries in the (...)
Request
Simulation tool

TINA-TI — SPICE-based analog simulation program

TINA-TI provides all the conventional DC, transient and frequency domain analysis of SPICE and much more. TINA has extensive post-processing capability that allows you to format results the way you want them. Virtual instruments allow you to select input waveforms and probe circuit nodes voltages (...)
User guide: PDF
View Options
Reference designs

TIPD117 — Dual-channel data acquisition reference design for optical encoders, 12 bits, 1 MSPS

This TI Precision Verified Design provides the theory, component selection, simulation, PCB design, and measurement details for a 12-bit 1-MSPS single supply dual channel simultaneous data acquisition system. This circuit achieves 73 dB SINAD for a 4.5 V differential signal at 2 KHz input (...)
User guide: PDF
Schematic: PDF
Reference designs

TIDM-ULTRASONIC-WATER-FLOW-MEASUREMENT — Ultrasonic Water Flow Measurement Reference Design

This Ultrasonic Water Flow Measurement system is ideal for providing highly accurate measurement across wide flow ranges as low as 1.4gpm. The design is based on a single MCU with discrete analog components. It uses a unique propriety algorithm that improves robustness and performance in flow (...)
Design guide: PDF
Schematic: PDF
Reference designs

TIPD115 — Data acquisition optimized for low distortion, low noise 18-bit 1-MSPS reference design

This verified design is a high performance data acquisition system (DAQ) using an 18-bit SAR ADC, ADS8881 at a throughput of 1MSPS. This design has been optimized to provide the lowest noise & distortion solution for a full scale input sinewave of 10 KHz. This leads to a maximum possible value (...)
User guide: PDF
Schematic: PDF
Reference designs

TIDA-00499 — Transient and Digital Fault Recorder AFE Using Differential Amplifiers and HS ADC Reference Design

While Digital Fault Recorders (DFRs) can detect transients in 17/20 μs at 60/50 Hz, transient recorders capture disturbances that can peak and decay well within a microsecond. This reference design demonstrates the capturing of transient inputs at up to 1 MHz for DFR and 25 MHz for (...)
Design guide: PDF
Schematic: PDF
Reference designs

TIDA-00715 — High Dynamic-Range Headphone Driver Reference Design for Voltage-Output, Differential Audio DACs

A low THD+N amplifier signal chain for driving headphones is presented. The design walks through various factors to consider in order to optimize performance based on customer needs.
Design guide: PDF
Schematic: PDF
Package Pins CAD symbols, footprints & 3D models
SOIC (D) 8 Ultra Librarian
VSSOP (DGK) 8 Ultra Librarian
TI's Standard Terms and Conditions for Evaluation Items apply.

Ordering & quality

Information included:
  • RoHS
  • REACH
  • Device marking
  • Lead finish/Ball material
  • MSL rating/Peak reflow
  • MTBF/FIT estimates
  • Material content
  • Qualification summary
  • Ongoing reliability monitoring
Information included:
  • Fab location
  • Assembly location

Support & training

TI E2E™ forums with technical support from TI engineers

View all forum topics

Content is provided "as is" by TI and community contributors and does not constitute TI specifications. See terms of use.

If you have questions about quality, packaging or ordering TI products, see TI support. ​​​​​​​​​​​​​​

Videos