The CC2650EM-4XS reference design contains schematics and layout files for the CC2650 Evauation Module with the 4x4 mm package and single-ended RF output with external biasing. The reference design demonstrates good techniques for CC2650 decoupling and RF layout. For optimum RF performance, the reference design, both schematic and layout, should be copied accurately.
There are several reference designs to choose from for the CC26xx device family, including designs with the various package types and also the different RF front-end options. All of the reference designs are with 2-layer PCB and has on-board PCB antenna.